Read e-book online A Practical Guide to Cluster Randomised Trials in Health PDF

By Sandra Eldridge

ISBN-10: 0470510471

ISBN-13: 9780470510476

ISBN-10: 1119966248

ISBN-13: 9781119966241

Cluster randomisedtrials are trials within which teams (or clusters) of people are randomly allotted to various sorts of remedy. In overall healthiness care, those trials frequently evaluate alternative ways of handling a disorder or selling fit residing, not like traditional randomised trials which randomise members to assorted remedies, classically evaluating new medicines with a placebo. they're more and more universal in healthiness prone study. This ebook addresses the statistical, functional, and moral matters coming up from allocating teams of people, or clusters, to diverse interventions.

 Key features: 

  • Guides readers during the phases of carrying out a tribulation, from recruitment to reporting.
  • Presents quite a lot of examples with specific emphasis on trials in overall healthiness providers examine and first care, with either ideas and methods defined.
  • Topics are in particular provided within the order during which investigators take into consideration concerns once they are designing an ordeal.
  • Combines details at the newest advancements within the box including a pragmatic consultant to the layout and implementation of cluster randomised trials.
  • Explains rules and methods via a variety of examples together with many from the authors personal adventure.
  • Includes quite a lot of references if you desire to learn further. 

This e-book is meant as a realistic advisor, written for researchers from the healthiness professions together with medical professionals, psychologists, and allied well-being pros, in addition to statisticians taken with the layout, execution, research and reporting of cluster randomised trials. people with a extra common curiosity will locate the abundant examples illuminating.

Chapter 1 creation (pages 1–21):
Chapter 2 Recruitment and Ethics (pages 22–43):
Chapter three Designing Interventions (pages 44–59):
Chapter four Pilot and Feasibility reports (pages 60–73):
Chapter five layout (pages 74–98):
Chapter 6 research (pages 99–136):
Chapter 7 pattern measurement Calculations (pages 137–171):
Chapter eight The Intra?Cluster Correlation Coefficient (pages 172–195):
Chapter nine different issues (pages 196–217):
Chapter 10 Trial Reporting (pages 218–265):

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Additional info for A Practical Guide to Cluster Randomised Trials in Health Services Research

Example text

Ard, J. et al. (2001) DASH (Dietary Approaches to Stop Hypertension) diet is effective treatment for stage 1 isolated systolic hypertension. Hypertension, 38, 155–158. , Zhanda, I. et al. (1997) Effect of a new antenatal care programme on the attitudes of pregnant women and midwives towards antenatal care in Harare. Cent. Afr. J. , 43, 131–135. M. (1998) Design and Analysis of Group Randomised Trials, Oxford University Press, New York. P. L. (2004) Design and analysis of group-randomized trials: a review of recent methodological developments.

2000) Evidence-Based Medicine: How to Practice and Teach, Churchill Livingstone, London. J. (2001) Contamination in trials: is cluster randomisation the answer? BMJ, 322, 355–357. J. J. (2008) Designing Randomised Trials in Health, Education and the Social Sciences, Palgrave Macmillan, Basingstoke. , Lamb, S. et al. (2011) The OPERA trial: protocol for a randomised trial of an exercise intervention for older people in residential and nursing accommodation. Trials, 12, 27. W. et al. (1975) Impact of a system of computer-assisted diagnosis: initial evaluation of the hospitalized patient.

5 Cost or administrative convenience In health services research, clusters are usually administrative units with participants who are located in a geographical area. Consequently there may be administrative reasons why it is easier to restrict the intervention to fewer clusters. , 1999), specialist nurses worked with the intervention practices to help integrate primary and secondary care of patients suffering from heart attacks. It would have been much more expensive to work with all practices.

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A Practical Guide to Cluster Randomised Trials in Health Services Research by Sandra Eldridge

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