By Craig Niederberger
An creation to Male Reproductive drugs is written in particular for readers looking access into this fast-moving, advanced strong point with an excellent realizing of the topic. the 1st chapters hide the anatomy and body structure, medical review, surgical procedure, medication, genetics and laboratory trying out all in favour of the present evaluate and remedy of the infertile male, and the ultimate bankruptcy describes the interplay of the sector with woman reproductive medication. in the course of the booklet, references are without delay made to the fourth version of the most important textual content within the distinctiveness, Infertility within the Male, edited via Larry Lipshultz, Stuart Howards and Craig Niederberger, permitting readers to extend their knowing of particular components the place wanted. each one bankruptcy is written by way of a well-renowned professional in a simple to persist with, casual variety, making the textual content perfect for college students, citizens and normal physicians who're looking to bring up their normal wisdom of the sector.
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Extra info for An Introduction to Male Reproductive Medicine
5] Padmanabhan V, Evans NP, Dahl GE, et al. Evidence for short or ultrashort loop negative feedback of gonadotropin-releasing hormone secretion. Neuroendocrinology 1995; 62: 248–58.  Bergendahl M, Evans WE, Veldhuis JD. Current concepts on ultradian rhythms of luteinizing hormone secretion in the human. Hum Reprod Update 1996; 2: 507–18. 27 28 Chapter 1: Male reproductive medicine: anatomy and physiology  Keenan D, Veldhuis JD. A biomathematical model of time-delayed feed-back in the human male hypothalamic-pituitary-Leydig cell axis.
According to anatomical location, the vas deferens is divided into scrotal, inguinal, and retroperitoneal portions. Histologic examination of the vas deferens reveals adventitial, muscular, and mucosal layers. The muscular coat consists of inner and outer longitudinal fibers separated by a middle circular layer. During seminal emission, relaxation of the circular layer causes lengthening. Conversely, contraction of the longitudinal layer produces shortening of the vas deferens. The net effect of these actions produces anterograde propulsion of fluid.
A small percentage of testosterone (~1%) is converted to dihydrotestosterone within the testes and elsewhere by isoenzymes 5a-reductase I and II, resulting in circulating dihydrotestosterone levels in the 1–3 nmol/liter range in healthy men. Dihydrotestosterone is thought to be a considerably more potent androgen than testosterone due to its 10-fold greater affinity for AR, but its role in spermatogenesis is not known. Transport Testosterone circulates in blood by binding to circulating plasma proteins.
An Introduction to Male Reproductive Medicine by Craig Niederberger